Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method.

نویسندگان

  • Nouruddin Wageih Ali
  • Maha Ahamd Hegazy
  • Mohamed Abdelkawy
  • Eglal Abdelahamid Abdelaleem
چکیده

Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in the presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results obtained were statistically compared with the reported HPLC methods; no significant difference between the proposed methods and the reported methods was found regarding either accuracy or precision.

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عنوان ژورنال:
  • Acta pharmaceutica

دوره 62 2  شماره 

صفحات  -

تاریخ انتشار 2012